8th International Conference of Orthopedic Surgeons and Rheumatology March 22-23, 2017 Rome, Italy

Yuxian Shen’s current research focused on the involvement of endoplasmic reticulum (ER) stress in the pathogenesises of neurodegenerative diseases and inflammatory diseases. The major findings in her lab are the results of protein degradation mediated by ER ubiquitin ligases of Hrd1 and gp78. Both of them facilitate degradation and enhance solubility of -1-antitrypsin Z mutant, a major cause of -1-antitrypsin deficiency. They also found that Hrd1 plays an important role in neuron protection. Additionally, Hrd1 promotes hyperphosphorylated tau degradation. An area of Shen’s lab is about ER stress-upregulated protein MANF. They found that MANF is sensitive to ischemia/hypoxia and inflammation. The results suggest that MANF may be involved in neuroprotection and inflammatory inhibition. Further efforts are directed to understand the transcription regulation of MANF under inflammation and ischemia. A new direction in her lab is to investigate the mechanisms of ER stress involved in autoimmune diseases including SLE and RA.

Yuxian Shen’s current research focused on the involvement of endoplasmic reticulum (ER) stress in the pathogenesises of neurodegenerative diseases and inflammatory diseases.

Professor El Miedany, graduated from Ain Shams University, Cairo, Egypt with an honor degree in 1984. He underwent early postgraduate training at the University Hospitals. He furthered his training in rheumatology at the Centre for Rheumatic Diseases, Royal Infirmary, Glasgow University; where he carried out his MD thesis about pulmonary affection in patients with rheumatoid arthritis and whether it is genetically related. Dr. El Miedany got Diploma in internal medicine, Master degree and MD in Rheumatology. Dr. El Miedany has been appointed Professor of Rheumatology and Rehabilitation, Ain Shams University, Egypt, since 2005. Currently he is honorary senior clinical lecturer, King’s college, London; and also Consultant Rheumatologist, NHS England. Prof. El Miedany is a fellow of the Royal College of Physicians (FRCP, London), American College of Rheumatology, British Society for Rheumatology and is a regional coordinator for the Paediatric Rheumatology International Organization (PRINTO).

He has special interest in Musculoskeletal Ultrasonography with wide experience in both diagnostic and US guided therapeutic procedures

Professor El Miedany, graduated from Ain Shams University, Cairo, Egypt with an honor degree in 1984. He underwent early postgraduate training at the University Hospitals. He furthered his training in rheumatology at the Centre for Rheumatic Diseases, Royal Infirmary, Glasgow University; where he carried out his MD thesis about pulmonary affection in patients with rheumatoid arthritis and whether it is genetically related. Dr. El Miedany got Diploma in internal medicine, Master degree and MD in Rheumatology. Dr. El Miedany has been appointed Professor of Rheumatology and Rehabilitation, Ain Shams University, Egypt, since 2005. Currently he is honorary senior clinical lecturer, King’s college, London; and also Consultant Rheumatologist, NHS England. Prof. El Miedany is a fellow of the Royal College of Physicians (FRCP, London), American College of Rheumatology, British Society for Rheumatology and is a regional coordinator for the Paediatric Rheumatology International Organization (PRINTO). Prof. El Miedany works closely with skilled and highly motivated medical colleagues and a team of dedicated musculoskeletal occupational and physiotherapists. This allows access to the full range of therapies available for simple and complex musculoskeletal disease including the Biologic therapies. He has special interest in Musculoskeletal Ultrasonography with wide experience in both diagnostic and US guided therapeutic procedures. He was an early proponent of the targeted treatment of inflammatory arthritis and the importance of measuring disease activity as well as patient reported outcomes in order to help guide treatment decisions. Prof. El Miedany has more than 200 publications published in international peer reviewed journals as well as elite conferences such as EULAR, ACR and BSR. He has been an invited speaker at many international rheumatology meetings and symposia worldwide. He authored/ co-authored several chapters in international rheumatology text books and has been the editor for 3 books, Publisher Springer. He is a reviewer for several international rheumatology journals and is associate editor for BMC: Musculoskeletal. His h-index is 20 and i10-index of 30. His has a research gate score of 40.17. His is currently working on a new book about “Comorbidity in Rheumatic Diseases” (Publisher: Springer). His website: www.rheumatology4u.com, provides specialized help to both patients suffering from variable rheumatic diseases as well as rheumatologists and specialist rheumatology nurses.

He has special interest in Musculoskeletal Ultrasonography with wide experience in both diagnostic and US guided therapeutic procedures

Dr. Zheng earned his PhD of Immunology at University of Orleans and French National Center for Scientific Research. He did his postdoctoral studies at UCLA and University of Southern California (USC). He was appointed as an Assistant Professor at USC in 2004 and has been a Full Professor of Medicine with tenure and director at Milton S. Hershey Medical Center at Penn State University since 2013. His expertise locates on the pathogenesis, cytokines, and immune regulation of autoimmune diseases. Dr. Zheng and his colleagues discover “induced regulatory T cells” and is a pioneer in the field of GMSC and immunoregulation

His expertise locates on the pathogenesis, cytokines, and immune regulation of autoimmune diseases.

Tao-Hsin Tung was born in Kaohsiung, Taiwan, in 1972. He received the BSC degree in Science from Medicine Sociology, Kaohsiung Medical University, Kaohsiung, Taiwan, in 1994, and the MSC in Science and Ph.D. degrees in Public Health, National Yang-Ming University, Taipei, Taiwan, in 1996 and 2005, respectively. In 2004, he joined the Department of Medical Research and Education, Cheng-Hsin General Hospital, as an Associated Researcher, and in 2008 became a Researcher. Since September 2006, he also has been with the Department of Public Health, College of Medicine, Fu-Jen Catholic University, New Taipei City, where he was an Adjunct Associate Professor. His current research interests include clinical epidemiology, biostatistics, disease screening and medical law.

His current research interests include clinical epidemiology, biostatistics, disease screening and medical law

Medical Consultant at U.O. Medicina Interna, Ospedale “Regina Apostolorum” in Albano Laziale (Rome, Italy), Responsible of the Internal Medicine – Rheumatology Ambulatory at Ospedale “Regina Apostolorum” in Albano Laziale (Rome, Italy) and Responsible of the Ostheoporosis prevention and therapy Ambulatory at Ospedale “Regina Apostolorum” in Albano Laziale (Rome, Italy). Author of 157 scientific publications including original articles on prominent italian and foreign journals such as “Reumatismo”, “Annali Italiani di Medicina Interna”, “Clinical Rheumatology”, “Annals of the Rheumatic Diseases”, “Osteoporosis International”, “Revista Española de Reumatologia”, “New trends in Experimental and Clinical Psychiatry”, “Clinical and Experimental Rheumatology”, “European Journal of Internal Medicine”

Rheumatology

Margaret Wisłowska, Head of The Department of Internal Medicine and Rheumatology CSK MSW is a specialist in internal medicine, rheumatology, rehabilitation medicine, hypertention, and the author of over 200 scientific papers and books. She has participated in numerous scientific meetings and is a promoter of 12 PhD theses. She took trainings at Guy and St. Thomas’ Hospitals in London, Charity Hospital in Berlin, Rheumatology Institutes in Prague and Moscow. In 2003, she started the Department of Internal Medicine and Rheumatology, and in 2010 the Clinic of Internal Medicine and Rheumatology CSK MSW. She is a Professor at the Warsaw Medical University.

Internal medicine, rheumatology, rehabilitation medicine, hypertention