Rheumatoid Arthritis

Rheumatoid arthritis is a chronic, systemic inflammatory disorder that primarily affects joints. It happens when the immune system attacks your own tissues and causes joint pain, swelling, and stiffness. It’s not part of normal aging.  It may result in deformed and painful joints, which can lead to loss of function. The disease may also have signs and symptoms in organs other than joints. The cause of rheumatoid arthritis is not completely understood. The process involves inflammation and fibrosis of the capsule around the joints. It also affects the underlying bone and cartilage. Treatments include both medication and non-pharmacological measures - the goal being to control joint inflammation and prevent joint damage and disability. The causes of Rheumatoid arthritis are not completely understood. Juvenile rheumatoid arthritis is the most common type of arthritis in children under the age of 17. It causes persistent joint pain, swelling and stiffness. Some children may experience symptoms for only a few months, while others have symptoms for the rest of their lives. Some types of juvenile rheumatoid arthritis can cause serious complications, such as growth problems and eye inflammation. A TNF inhibitor is a pharmaceutical drug that suppresses response to Tumour (TNF), which is part of the inflammatory response. It is used in the treatment of rheumatic arthritis. Gene expression has recently been at the forefront of advance in personalized medicine, notably in the field of cancer and transplantation, providing a rational for a similar approach in rheumatoid arthritis. While Disease-Modifying Anti-Rheumatic Drug (DMARD) Therapy also have high impact for Active Rheumatoid Arthritis.

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