Scleroderma
Scleroderma is a cluster of autoimmune diseases that will lead to changes to the skin, blood vessels, muscles and internal organs. The illness will be either localized to the skin or involve alternative organs, as well. Symptoms could embody areas of thickened skin, stiffness, feeling tired, and poor blood flow to the fingers or toes with cold exposure. One variety of the condition, called CREST syndrome, classically leads to Ca deposits, Raynaud's syndrome, esophageal issues, thickening of the skin of the fingers and toes, and areas of tiny, dilated blood vessels
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